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301 In addition, SGLT-2i still showed a remarkable cardiovascular benefit in nondiabetic patients, indicating that SGLT-2i had a blood glucose-independent effect on improving cardiovascular outcomes

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GLP-1 RAs in Steatotic Liver Disease (MASLD, MetALD, and ALD) Although not yet specifically approved for the treatment of MASLD, GLP-1 RAs exhibit pleiotropic effects that contribute to the improvement of MASLD and its progression to metabolic dysfunction-associated steatohepatitis (MASH) (Table 3)

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10.1016/j.ijbiomac.2019.10.010 85 LiL.LiR.-C.SongY.-H.WuW.-Y.YinS.-H.FuW.-W.et al (2019b)

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