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PCOS is an endocrine (hormone) condition where blood sugar dysregulation worsens the hormonal imbalances that cause symptoms like weight gain, acne, irregular periods, and unwanted hair growth

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Elevated homocysteine has been associated with cardiovascular disease, stroke, and impaired blood vessel function, making methylation an important contributor to cardiovascular health

Genetic backgrounds may also influence patients responses to specific drugs, with certain genetic variations potentially leading to differences in sensitivity to DMARDs or biologic agents