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Initially identified as nine fundamental biological drivers of aging (13), the list has been updated to include twelve hallmarks: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis (14)

Prevalence of hematologic complications on extracorporeal membranous oxygenation in critically ill pediatric patients: A systematic review and meta-analysis

Insomnia and dry mouth round out the less common but notable side effects

While most people tolerate the infusion well, some might experience mild side effects such as a cooling sensation during the infusion or a slight taste of vitamins in their mouth, which are generally transient and not cause for concern