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clinical trials showed modest but statistically significant weight loss (approximately 2.6 kg vs

Other stimuli that enhance calcitonin secretion include supraphysiologic concentrations of glucagon (48), 5HT1 receptor agonists (49) gastrin (and pentagastrin) (50), alcohol (51), and exercise (52) and glucagon-like peptide-1 (GLP-1) (53) A detailed discussion of each of these stimuli is beyond the limits of this chapter and the reader is referred to a review on this subject for more detail (54) The finding that glucagon-like peptide-1 (GLP-1) agonists, an effective therapy for type 2 diabetes mellitus, bind to GLP-1 receptors, stimulates CT release and cause MTCs in rodents has stimulated a broad discussion regarding their safety in humans (53)

One of the most promising approaches involves regenerating hair cells in the inner eartiny sensory structures responsible for detecting sound

After 2 weeks, increase the dose to 20mg/day