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In pMCAO, serum nitrite levels were not significantly changed
Because embryonic stem (ES) cells give rise to all the tissues in an organism, mechanisms are in place to avoid the accumulation of DNA to prevent mutations that would transmit to tissues and subsequent generations
In SCD, HU has a multimodal effect that aids in enhancing HbF production, delaying HbS polymerization, which also lessens hemolysis, increasing NO availability, thereby aiming at cGMP production, and aiding in the regulation of endothelial activation and neutrophil accumulation, thereby reducing inflammatory processes
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