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With consistent follow-through, patients often lose 5% to 15% of their starting body weight within 3 to 6 months

Unique mapped reads were counted using SAMtools by filtering the aligned reads in the BAM files

It is therefore troublesome to provide a unifying mechanism describing how familial PD-associated mutations affect the structure of -synuclein, and how their accumulation and function link with PD, as there have been several suggestions pointing in this direction [21]