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Thus, more efforts are needed to increase folate production levels through metabolic engineering 1,631,632,634,635

Therefore, from a genetically inherited perspective, we used MR and SMR methods, supported by the huge data from public databases, to dig deeper into the association between GLP-1R gene expression in blood tissues (mimicking the effect of GLP-1RA) and the risk of DR in European populations

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The majority of Chinese participants were male (80.0%), while the proportions of male and female Caucasian participants were roughly equal (53.3% and 46.7%, respectively) (Table 1)