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Peptides function as signaling molecules that influence cellular processes, which distinguishes them from steroids (lipid-based hormones derived from cholesterol) and SARMs (selective androgen receptor modulators that target androgen receptors)

Compared with the overall resolution of the nanobody-bound structure (3 ) the local resolution at the nanobody binding site was in the range of 2.32.8 (Extended Data Fig

Mol Metab 32:4455 Frias JP, Nauck MA, Van J, Kutner ME, Cui X, Benson C et al (2018) Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial

Applied to longevity, this could mean focusing on key biomarkers and lifestyle changes for maximum impact