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The approaches of FMT and probiotics are in their early stages

Astrocytederived glutamine (Gln) serves as a precursor for the glutamate (Glu) needed by neurons for GSH synthesis

Another important substance, bile acid (BA) metabolites, are produced by microbial biotransformation of BA that pass through the enterohepatic circulation, which plays an important role in regulating intestinal inflammation by regulating immune cell maturation and cytokine release through farnesoid X receptor (FXR) and G protein-coupled receptor 5 (TGR5) receptors [117, 118]

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