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Some individuals also opt for one-time B12 shots to give themselves an extra boost during particularly busy or stressful times in their lives.

A knockdown study and a small-molecule mouse study are exactly the steps that should precede a human trial, and they are the reason a compound gets taken seriously enough to be studied further

In a review of studies, researchers found that while vitamin B12 supplementation did not improve depressive symptoms, low vitamin B12 levels were linked to an increased risk of developing depression