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Patches stick more successfully to thin-skinned spots with an abundance of blood supply, like the inner wrist, upper arm, lower back, or behind the ear, he says, while ineffective spots include the soles of your feet or areas where hair would prevent the patch from sticking properly

Unfortunately, this can lead to something of a self-fulfilling prophecy one that leaves you reaching for more caffeine in a desperate bid to delay these caffeine crash symptoms

These compounds are often obtained through unregulated sources that may lack quality control standards

No evidence suggests harm, but definitive evidence of long-term safety does not exist either