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Ethics statement The animal study was reviewed and approved by Xiangya Hospital Central South University
Important questions include Whether long term use is anticipated What is known about discontinuation How maintenance is approached if therapy changes Follow up analyses from randomized controlled trials show that discontinuing GLP 1 therapy is commonly associated with a return toward baseline weight or metabolic set point
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The comparison is therefore partly apples-to-oranges: retatrutide is a finished multi-mechanism molecule, whereas cagrilintides headline performance depends on the partner it is combined with
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