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The compound also increases IGF-1 levels consistently, supporting muscle protein synthesis and recovery

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Introduction Diabetes mellitus (DM) is a common non-communicable disease that affects the global population, including an estimated 11.6% of the Chinese adult population ( T2DM is characterized by insulin resistance and lesions of pancreatic beta cells, resulting in a worsening glycaemic control and an increasing use of antidiabetic drugs including insulin ( Glucagon-like peptide-1 (GLP-1) is an incretin hormone that is secreted from intestinal L-cells and circulates through the ingestion of nutrients ( Peroxisome proliferator-activated receptor alpha (PPAR) is a ligand-activated transcription factor of the NR1C nuclear receptor subfamily ( GLP-1 receptor (GLP-1R) is present on human hepatocytes ( In this study, Zucker diabetic fatty (ZDF) mice were treated with the combination of liraglutide and insulin