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Safety outcomes: examined odds of hypoglycemic events using administrative codes validated in prior studies 55,56 and gastrointestinal symptoms (constipation, diarrhea, change in bowel habits, abdominal pain, or ileus) during follow up period using administrative codes, as described in prior publications 57

405,600,601,602 These findings underscore the importance of itaconate in immune modulation and metabolic reprogramming, highlighting its potential in liver repair