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After 28 days mice were sacrificed and fresh striata were dissected for dopamine and 1-methyl-4-phenylpyridinium (MPP + ) analysis and midbrains were fixed in 4% paraformaldehyde for immunohistochemistry staining

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TdGSH prevented LOsG-induced functional failure of dedifferentiated -cell via the FoxO1/TXNIP pathway Pancreatic -cell dedifferentiation is one of the mechanisms resulting in diabetic -cell failure