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Anti-Cancer Agents Med Chem (formerly Current Medicinal Chemistry-Anti-Cancer Agents) 14:10941100 Das S, Al-Toubah T, El-Haddad G, Strosberg J (2019) 177Lu-DOTATATE for the treatment of gastroenteropancreatic neuroendocrine tumors

Metformin further enhances oxidative stress resistance via upregulation of Klotho and GDF-15, promoting mitochondrial efficiency and anti-senescence signaling (Zhang et al., 2012)

That means fertility may increase, sometimes unexpectedly, and women should be counseled regarding this. To prevent pregnancy you should use reliable birth control while taking GLP-1s, she says