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Researchers associate a vitamin B12 deficiency with various health issues, megaloblastic anemia neurological changes and disorders infertility depression neural tube defects and developmental delays in children born to those with a vitamin B12 deficiency Supplementation may help to reduce the risk of these health issues

It warned in November 2023 that potent prescription medicine should not be shared with or supplied to others, even if medical conditions appear to be similar

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A 2025 systematic review of BPC-157 in orthopedic applications confirmed improved structural, functional, and biomechanical outcomes across muscle, tendon, ligament, and bone injuries in 36 studies