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Statistical significance was assessed by one-way ANOVA followed with Dunnets multiple comparisons test in d, q , by ordinary two-way ANOVA followed by dks multiple comparisons test in e , r , and by ordinary two-way ANOVA followed Tukeys multiple comparisons test in j-o

In a mouse model, treatment was shown to limit the rise in syndecan-1, the main marker of endotheliopathy [141], and to help maintain glycocalyx thickness (intravital microscopy) in treated animals with HS

Researchers were interested in investigating the potential variations in the effectiveness of metformin treatment among different stages of adolescence and phenotypes

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