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Several factors combine: absence of active patent (thus little pharmaceutical incentive to finance trials), ambiguous regulatory status in most countries, high cost of a phase I to III clinical trial (several million to tens of million euros), difficulty in defining a precise indication acceptable to a regulatory authority

The compound combines GLP-1 receptor agonism with GIP receptor antagonisma novel mechanism informed by human genetics research suggesting GIP inhibition as a key factor in reducing body mass [44]

The drip supports the biology

All three peptides act as growth hormone secretagogues , meaning they stimulate the pituitary gland to release GH without introducing synthetic growth hormone