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The treatment group had better verbal fluency test scores after six weeks.[ref] Other studies also showed mild efficacy for creatine in bipolar disorder.[ref] Cognitive function in young adults: Not a big benefit Clinical trial results dont show much of an effect of creatine supplementation on cognitive processing speed in healthy young adults.[ref] One trial did show a small beneficial effect in healthy young adults, with half of the participants being vegetarians.[ref] Cognitive function in older adults: Beneficial A clinical trial using 5g four times a day for a week showed a significant improvement in cognitive function test scores.[ref] The opposite results for healthy younger people vs

Prevention of Future Side Effects: After experiencing a side effect, steps should be taken to prevent recurrence

doi: 10.1016/j.cmet.2023.11.009 [DOI] [PubMed] [Google Scholar] 82

Green JB, Bethel MA, Armstrong PW et al (2015) Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes