Medical Conditions: Sometimes, underlying medical conditions like thyroid problems or autoimmune diseases can trigger hair loss
NOT Appropriate for Acute Injuries Requiring Medical Intervention: Fractures, severe sprains, traumatic injuries, and conditions requiring immediate medical attention should be evaluated and treated by healthcare professionals
However, difficult to detect does not mean undetectable. Testing technology continues improving rapidly
The antiproliferative effect of calcitriol involves multiple pathways, such as the expression of cyclin-dependent kinase inhibitors (i.e., CDKN1A and CDKN1B), the production of growth factors (i.e., TGF-, IGF) and miRNAs, the regulation of cancer stem cell proliferation, tumor angiogenesis, epithelial-mesenchymal transition, and the activation of caspases (49, 5356)