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*Correspondence: Li Chen, [email protected] This article was submitted to Gut Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Under cysteine-limiting conditions, Glu is recycled into Glu (a futile cycle) via 5-oxoprolinase at the expense of two ATP molecules without GSH production and this is the reason for the decrease in GSH synthesis as well as the depletion of ATP in these cells [14]

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Mehmet Oz, who had just spoken, jumped to attention and quickly rushed over to help as those standing around him grabbed the man before he hit the ground