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Leistner, C & Menke, A Hypothalamic-pituitary-adrenal axis and stress, in Sex Differences in Neurology and Psychiatry Handbook of Clinical Neurology 55-64 (2020), 175

Consequently, intracellular zinc homeostasis alterations regulate downstream molecular objectives, in addition to protein kinase C (PKC), ERK1/2 activation leading to neuronal cell death, cAMP-dependent protein kinase (PKA), Ca/calmodulin-dependent protein kinase II (CaMKII), phosphodiesterases (PDEs), protein tyrosine phosphatases (PTPs), and transcription factors, such as NF-B

[6] Vanotti A, Osio M, Mailland E, Nascimbene C, Capiluppi E, Mariani C

deficiency is associated with increased cramping risk, and IV magnesium is a standard clinical treatment for specific conditions (notably eclampsia)