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Butyrate functions as a broad-spectrum modulator of PTMs, regulating modifications (acetylation, crotonylation, and butyrylation) on histone and non-histone proteins, while influencing non-histone substrates ubiquitination

Topical cyanocobalamin is used to treat skin irritation and atopic dermatitis

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Furthermore, IP analysis indicated that the PGK1 Kcr level decreased under hypoxia and depletion of ECHS1 completely eliminated the effect on PGK1 Kcr induced by hypoxia (Fig