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In the next step, we performed clumping to reduce the impact of strong linkage disequilibrium, including only SNPs with weak linkage disequilibrium (r 0.05) (Table 3)

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Las recientes normativas de la American Diabetes Association (ADA) 55 , las guas conjuntas de la European Society of Cardiology (ESC) y la European Association for the Study of Diabetes (EASD) 56 , la gua de prctica clnica del programa Kidney Disease: Improving Global Outcomes (KDIGO) 17 y las Guas de la Asociacin Latinoamericana de Diabetes (ALAD) 56 incluyen recomendaciones al respecto que se sintetizan en la Tabla 3