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A randomized, controlled clinical trial with liraglutide showed a 38% decrease (from a baseline of 40.6 38.6 ng/l) in brain natriuretic peptide, a marker of left ventricular dysfunction (225)

Yes, there is no known direct pharmacological interaction between melatonin and Wegovy, and taking them together is generally considered safe for most individuals

These benefits may take a few months to become evident, as the medication works to improve overall cardiovascular health by lowering blood pressure, reducing inflammation, and improving lipid profiles