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Here is what the medication is, how local availability differs from telehealth Retatrutides phase 2 trial produced an average of about 24% body weight loss, higher than the numbers seen with approved medications like tirzepatide and semaglutide.

Semaglutide works by targeting a single hormone (GLP-1), helping reduce appetite and improve blood sugar control, while tirzepatide targets two hormones (GLP-1 and GIP), which may lead to greater appetite suppression and weight loss for some patients

A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis

Additionally, weight-loss medications are typically most effective when used as part of a comprehensive weight-management program that includes dietary changes, physical activity, and behavior changes