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143 Intriguingly, lactylation of HDAC indirectly regulates RNA methylation by modulating the expression of RNA methylation-related enzymes

Rat-to-human scaling is notoriously unreliable for cognitive compounds

Frontal areas are critical for top-down cognitive modulation of pain and pain-related emotions (Thompson and Neugebauer, 2019)

This implies that administering an anti-ferroptotic agent too early (during ischemia) may be futile, whereas delayed treatment misses the peak window of lipid peroxidation damage