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Results: At 48 weeks, there was no difference in liver stiffness (primary endpoint) between the sema and PBO groups (MRE, estimated treatment ratio (ETR) [95%CI]: 0 .96 [0 .89-1 .03], p=0 .2798), and no difference in liver stiffness was observed at week 72
Current evidence suggests a modest uric acid-lowering effect may occur, though findings remain inconsistent and the mechanism is not fully understood
Retatrutide is an investigational peptide that has completed phase II clinical trials, with phase III trials underway or in planning
Malik S, Saeed S, Saleem A, Khan MI, Khan A, Akhtar MF
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