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Safe under supervision for approved indications, but off-label use increases risks

Entre personas sin trastorno previo por consumo de sustancias, quienes tomaban GLP-1 tuvieron un riesgo 18% menor de desarrollar trastorno por consumo de alcohol, 25% menor de desarrollar trastorno por consumo de opioides y cerca de 20% menos riesgo de dependencia a la cocana y la nicotina

In May, Novo Nordisk agreed a partnership deal with Septerna to jointly discover and develop multiple oral small molecule obesity and cardiometabolic disease drugs