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Ramirez-Carrozzi et al., 2009)

Among the proteins with increased expression in ME/CFS were 3-hydroxybutyrate dehydrogenase type 1 (BDH1) and acetyl-CoA acetyltransferase 2 (ACAT2), both of which are integral to fatty acid metabolism and processing of ketone bodies

Combine processed diets and alcohol, and you have a combination that depletes glutathione faster than the body can replenish it, leaving the cells vulnerable to free-radical attack and chronic inflammation