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Unlike other weight-loss injections, retatrutide activates GLP-1, GIP, and glucagon receptors simultaneously, whereas typical injections target one or two of these receptors

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Your healthcare provider will have to inform Cigna that you have performed behavioral modifications (e.g., increasing exercise) and a reduced-calorie diet for at least three months, and have either: A BMI of 30 or higher, or A BMI of 27 or higher, plus a weight-related comorbidity approved by Cigna, such as hypertension, Type 2 diabetes, dyslipidemia (high cholesterol), obstructive sleep apnea, or cardiovascular disease Wegovy is also FDA approved for cardiovascular risk reduction