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Ketamine, a dissociative anesthetic, works along the glutamate pathway and has shown promise as a potential treatment for severe depression in small doses.80 In nootropic supplements, caffeine, cocoa, theobromine, and L-theanine may influence glutamate
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There are several pharmacological treatments available to augment insulin secretion or reduce peripheral tissue insulin resistance in addition to patients adopting a healthier diet and increased exercise to achieve weight loss, which promotes normoglycaemia and alleviates the disease phenotype
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