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Tirzepatide causes gastrointestinal side effects (nausea, vomiting, diarrhoea) in 3045% of patients during dose titration, typically resolving within 48 weeks
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c , Top, volcano plot showing relative fold change (log 2 ) in ER-metabolite abundance versus log 10 (P value) from ER-tag HEK293T cells treated with antimycin compared to untreated
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