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5.1 Preserving the GSH/GSSG Redox State Across Sample Matrices Preanalytical oxidation is a major source of error in GSH/GSSG analysis

The studies performed in subjects with chronic exposure to arsenic [27], or with clinically relevant intoxication by mercury [76], and in experimental animals intoxicated by mercury [77], cadmium and lead [78] show that the levels of some indicators of oxidative stress are displaced towards a pro-oxidative condition

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In diabetics and patients with renal insufficiency, the excretion of carnitine is increased