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Furthermore, it remains controversial whether agonists or antagonists of the GIP receptor are the optimal approach in the management of metabolic disorders (73)

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Ozempic's once-weekly injection schedule, its demonstrated 1.5-1.8% HbA1c reduction, and the SUSTAIN cardiovascular outcomes trial data showing 26% reduction in major cardiovascular events in T2DM patients with established cardiovascular disease collectively built a clinical case that endocrinologists and cardiologists find compelling for guideline-aligned prescribing