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Some websites may estimate that retatrutide could become available in 2027 or 2028, but this has not been confirmed

However, combining these medications should be done under strict medical supervision to avoid potential risks such as hypoglycemia, where blood sugar levels drop too low

HMG-CoA reductase inhibitors (statins) to reduce cellular production of cholesterol Medications to lower cholesterol absorption from the intestine (eg bile acid sequestrants like colesevelam) PCSK9 inhibitors, which allow LDL to bond to its receptors and be removed from the blood For people who require additional LDL lowering, the new drug bempedoic acid may be recommended in addition to statin therapy

See the Cagrilintide protocol page for the standalone reference