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1 mg / 0.5 ml

Standard escalation protocol from clinical trials The Phase 2 trial published in the New England Journal of Medicine tested several dose groups

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However, when following a weekly wound care protocol which included clinic visits (sharp debridement, compression dressing application, and wound measurement) alongside home TWO 2 therapy application 5-7 days/week for up to 90 minutes/session (per the manufacturers protocol), all patients achieved 100% healing/epithelialization