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In another human study, Epitalon was applied to PHA-stimulated lymphocytes from adult donors aged 25 to 88 years

Lysyl oxidase (LOX)mediated collagen cross-linking further increases ECM rigidity, which in turn activates integrinFAKYAP/TAZ and Wnt/-catenin signaling pathways, and promotes epithelialmesenchymal transition (EMT) and fibrogenesis (126)

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Zh.Nevrol.Psikhiatr.Im S.S.Korsakova 2008;108(9):36-40