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Huang H-Y, Appel LJ, Choi MJ, et al

However, when the body is subjected to severe viral infections, environmental toxins, or chronic inflammation, this ratio can plummet dramatically, indicating that the cellular defense systems are overwhelmed and failing to keep pace with the influx of free radicals

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Niacinamide discontinuation offers comparison to another well-tolerated ingredient supporting skin barrier function, reducing inflammation, and providing multiple anti-aging benefits through gentle mechanisms rather than aggressive stimulation