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The FDA-approved, branded versions of GLP-1 products were so popular that the brand manufacturers were not able to keep up with demand, prompting the FDA to declare a shortage for each of the semaglutide and tirzepatide products over the course of 2022

Medicaid programs in North Carolina, South Carolina, Michigan, New Hampshire, and California have announced plans to eliminate or narrow access to GLP-1 weight-loss treatment in some cases limiting it only to people who are morbidly obese. The reversal reflects tightening budgets, slowing revenue growth, and rising spending demands

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Besides the compounders, Wegovy continues to face formidable competition from Eli Lillys Zepbound, whose own growth appears to have no bounds