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The most frequently used method of siloplasty is associated with a fairly high incidence of adhesive disease, moreover, in some cases it is not possible to reduce the defect in a sufficiently short time, and the time frame for the presence of the siloplasty bag should not exceed 5 days (83)

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As presented in Figure 2, the magnitude of ROS production in melanocytes in vitiligo patients is due to a high electrical potential in mitochondrial intermembrane space (Schlame and Greenberg, 2017)

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