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Jawless fish (e.g., the lamprey Petromyzon marinus ) (18) and teleost fish (e.g., zebrafish ( Danio rerio ) and anglerfish ( Lophius americanus )) (16, 19, 20) are a pair of lineages that have duplicated Gcg genes, where in both lineages one of the duplicated genes has lost an exon that encodes a glucagon-like peptide (the GLP-1 encoding exon in lamprey and the GLP-2 encoding exon in teleost fish)

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Eric Xu et al., Structural insights into the peptide selectivity and activation of human neuromedin U receptors

42, D1147D1153, doi: 10.1093/nar/gkt1191 (2014)