Delta sleep-inducing peptide (DSIP): a review Graf MV, Kastin AJ Neuroscience and Biobehavioral Reviews (1984) This foundational review comprehensively analyzed the first decade of research on Delta Sleep-Inducing Peptide since its discovery in 1977, examining the evidence for its sleep-modulating, stress-protective, and neuroendocrine effects across numerous animal and human studies
Vitamin B12 has a good safety profile, but some important considerations include rare hypersensitivity reactions (including anaphylaxis) with injections, potential hypokalaemia during early treatment of severe deficiency, and possible cutaneous reactions
Furthermore, this study reported that mice exposed to three days of dLAN post MCAO increased TNF-, IL-6, and IL-1 in the ipsilateral hemisphere of the brain, and displayed increased anxiety-like behavior compared to control mice (Weil et al., 2020)
In one study, BPC-157 was shown to reduce brain swelling and inflammation with topical application in rats with superior sagittal thrombosis
