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The specificity and efficiency of TR knockout was confirmed, as evident from the significantly decreased mRNA levels of Thrb in the liver but not in the adipose tissues, muscle, heart, and ileum of LTRKO mice (Supplementary Fig

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Side effects are typically mild and may include redness or swelling at the injection site, headaches, or digestive discomfort

Weeks 812+: The Collagen Remodeling Window Significant reductions in deeper wrinkles, increased collagen density, and clearer, more resilient skin are commonly observed