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F.GengY.et al (2023)

aOoC models advance this approach by incorporating patient-specific cells, deriving from biopsy tissues, thereby creating personalized systems that more precisely reflect an individuals unique physiology and pathology

Although several preclinical anti-cancer outcomes have been achieved, such as with ferroptosis inducers, translating oxidative cell death mechanisms into effective clinical therapies requires rigorous testing, including assessments of bioavailability, toxicity, and off-target effects

Glutamate donates the nitrogen for the transamination step in serine biosynthesis, which can supply both glycine and cysteine for glutathione production