Viral-Hijacked Human Furin SARS-CoV-2, the etiological agent of COVID-19 pandemic, contains a unique insertion of amino acids (AAs), exclusively proline- arginine -arginine-alanine- arginine (P R RA R 685 ) at the S1/S2 boundary of its S-protein, which is clearly absent in SARS-CoV and other related hCoVs 72
Its noteworthy that previous studies extensively documented the pharmacological properties of durian fruit pulp extract, including its antiproliferative 30,31,32,33,34 , neuroprotective 35 , and antidiabetic 32 activities on human cell lines
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doi: 10.1093/hmg/ddaa028 176 MengHYamashitaCShiba-FukushimaKInoshitaTFunayamaMSatoSet al
