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Constipation: Duration data is less well-characterized, but clinical experience suggests constipation may persist longer than other GI side effects, sometimes requiring ongoing management strategies throughout treatment

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This is higher than standard keto recommendations but necessary to counter the elevated lean mass loss associated with GLP-1-driven caloric restriction

Special Considerations for Women Women, in particular, may respond differently to fasting depending on their menstrual cycle, hormone health, or stress levels