falciparum standard in vitro culture conditions were conducted as previously described ( Eryptosis Assay and Flow Cytometry Analysis Previously described eryptosis inducers were selected for this study based on their use (or potential use) in the clinic, their known targets and/or their previously described antimalarial activity ( Table 1 ): amiodarone HCl (Selleck Chem, #S1979), apigenin (Selleck Chem, #S2262), BAY 43-9006 (AdipoGen Life Sciences, #AG-CR1-0025), benzethonium chloride (Selleck Chem, #S4162), cordycepin (Cayman Chemicals, #14426), ionomycin (ThermoFisher, #I24222) and oridonin (Selleck Chem, #S2335)
Medical Supervision required for all protocols Custom Individualized dosing and monitoring plans Questions Senescent cells are aged, dysfunctional cells that have stopped dividing but resist normal cell death
Paulose B et al (2013) A -Glutamyl cyclotransferase protects Arabidopsis plants from Heavy Metal Toxicity by Recycling Glutamate to maintain glutathione homeostasis
For example, five 40mg vials would normally cost 483,000, but with the bulk discount you'd pay around 410,550
