Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men
Maintenance of nervous system health
Molecular Characteristics Complete Specifications: Molecular Weight: 1,815.08 Da Molecular Formula: CHNOS Amino Acid Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Peptide Length: 16 amino acids Peptide Classification: hGH C-terminal fragment (176-191), modified with Tyr177 Disulfide Bond: Cys7-Cys14 (corresponding to Cys182-Cys189 in hGH) Appearance: White to off-white lyophilized powder Solubility: Water, bacteriostatic water, phosphate buffered saline The peptides 16-amino acid structure corresponds to the C-terminal region of human growth hormone with a single modification: tyrosine replaces phenylalanine at position 177 (position 1 in the fragment)
This follows its role as a cytoprotection mediator transmitting the mucosal integrity maintenance to other organs therapy [1,2,3,4,5,6,7,8,9,10,11,15,27,28,29,30,33,109,124,125] in consideration of the regular dietary taking (dietary nitrate as an important source of NO in mammals [252]), and nitrate-nitrite-NO pathway (and swallowed nitrite) resulting with high NO concentration in the stomach [253]
